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Mashup Score: 1
Patients with chronic spontaneous urticaria (CSU) have spontaneous wheals (W), angioedema (AE), or both, for longer than 6 weeks. Clinical differences between patients with standalone W, standalone AE, and W and AE (W+AE) remain incompletely understood.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Chronic or recurrent Campylobacter enteritis in primary immunodeficiency: A UK national case-series and review of the literature - 2 year(s) ago
Campylobacter infection, usually by Campylobacter jejuni, is the most common cause of bacterial enteritis in the world. In healthy individuals, the infection is self-limiting, but in patients with immunodeficiency, recurrent or persistent symptomatic infection may occur. In this case series, we present a cohort of primary immunodeficiency patients with chronic or recurrent Campylobacter enteritis from the United Kingdom and review the previously published literature.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 12
AbstractBackground and Aims. Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study aims to descr
Source: academic.oup.comCategories: Cardiologists1, Latest HeadlinesTweet
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Mashup Score: 27
AbstractBackground and Aims. Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study aims to descr
Source: academic.oup.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Most Patients With Autoimmune Chronic Spontaneous Urticaria Also Have Autoallergic Urticaria, but Not Vice Versa - 2 year(s) ago
Two endotypes of chronic spontaneous urticaria (CSU) associated with mast cell–activating autoantibodies are described, namely autoallergic chronic spontaneous urticaria (aaCSU; with immunoglobulin E [IgE]–anti-autoallergens) and autoimmune chronic spontaneous urticaria (aiCSU; with IgG–anti-high-affinity receptor for the Fc region of immunoglobulin E [FcεRI]/IgE).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1
Omalizumab is the only biological agent approved for patients with chronic spontaneous urticaria (CSU), but no biomarker is well established for predicting clinical response to omalizumab.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Chronic Spontaneous Urticaria: The Role and Relevance of Autoreactivity, Autoimmunity, and Autoallergy - 2 year(s) ago
Chronic spontaneous urticaria (CSU) is a frequent and often severely disabling disease. A large number of studies were performed during the last 2 decades to clarify its pathogenesis. These studies shed light on the underlying autoimmune mechanisms of CSU pathogenesis and have led us to understand that different mechanisms may exist and, sometimes, coexist behind the same clinical presentation. The present article reviews the meaning of the terms autoreactivity, autoimmunity, and autoallergy, which have been variably used over the years to define different endotypes of the disease.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Taming the Flame of Aging: Key Pathway for Chronic Inflammation Revealed - Neuroscience News - 2 year(s) ago
Researchers have unveiled the key role of the cGAS/STING molecular signaling pathway in driving chronic inflammation and functional decline during aging.
Source: neurosciencenews.comCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 0Managing Chronic Urticaria and Angioedema: Novel Insights - 2 year(s) ago
Chronic urticaria and angioedema are recurrent conditions that significantly impact patients’ quality of life. Over the past 2 decades, extensive research has been conducted to elucidate the underlying mechanisms and improve the management of these conditions. Recent investigations of the pathophysiology of chronic spontaneous urticaria (CSU) have highlighted the role of autoimmune mechanisms, and 2 endotypes have been characterized: type I autoallergic CSU, associated with immunoglobulin E (IgE) antibodies against autoantigens, and type IIb autoimmune CSU, driven by autoantibodies that activate mast cells, including anti- FcεRI (high-affinity receptor for the Fc region of IgE) and anti-IgE.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 4Chronic Urticaria and Angioedema: Masqueraders and Misdiagnoses - 2 year(s) ago
Chronic urticaria is a common condition presenting with intensely pruritic wheals. Although individual lesions resolve within 24 hours, by definition, chronic urticaria lasts for a duration of at least 6 weeks. Both spontaneous and inducible forms exist. In the spontaneous variant, chronic urticaria occurs in the absence of clearly identifiable triggers. In chronic inducible urticaria, specific triggers may include dermatographism, cholinergic (heat), cold, exercise, delayed pressure, and solar.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
In Press! #Patients With #Chronic #Spontaneous #Urticaria Who Have #Wheals, #Angioedema, or Both, Differ #Demographically, #Clinically, and in #Response to #Treatment— #Results From CURE https://t.co/vTsthjkW1k https://t.co/XcFjr5ndwc