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    Ability of a polygenic risk score to refine colorectal cancer risk in Lynch syndrome - 2 year(s) ago

    Background Polygenic risk scores (PRSs) have been used to stratify colorectal cancer (CRC) risk in the general population, whereas its role in Lynch syndrome (LS), the most common type of hereditary CRC, is still conflicting. We aimed to assess the ability of PRS to refine CRC risk prediction in European-descendant individuals with LS. Methods 1465 individuals with LS (557 MLH1 , 517 MSH2/EPCAM…

    Source: Journal of Medical Genetics
    Categories: General Medicine Journals and Societies, Latest Headlines
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      JMG_BMJ

      There is variability in #BowelCancer age within #LynchSyndrome families 📈 New study shows there is only WEAK association between #PRS & multiple/young cases ➡️ https://t.co/pHV317AYQz @NDuenas5 @BrunetJbrunet @hannah_klink @MartaPinedaRiu @geneticcounsel @LValleResearch https://t.co/G68j5tubxU

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    Wolters Kluwer Health - 2 year(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

    Source: lww.com
    Categories: Hem/Onc News and Journals, Latest Headlines
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      OncologyTimes

      A new library documenting mutations can help explain why some #cancers don't respond to #immunotherapies. Researchers from @sangerinstitute used #CRISPR gene editing technology and mini tumors to understand the role of mutations in #bowelcancer cell lines: https://t.co/b2qukYv0Ez https://t.co/8M1kQsxLFp

  • Mashup Score: 1
    Wolters Kluwer Health - 2 year(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

    Source: lww.com
    Categories: Hem/Onc News and Journals, Latest Headlines
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    • Profile photo of OncologyTimes
      OncologyTimes

      A new library documenting mutations can help explain why some #cancers don't respond to #immunotherapies. Researchers from @sangerinstitute used #CRISPR gene editing technology and mini tumors to understand the role of mutations in #bowelcancer cell lines: https://t.co/b2qukYvyu7 https://t.co/oJvGpLczmc

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    Wolters Kluwer Health - 2 year(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

    Source: lww.com
    Categories: Hem/Onc News and Journals, Latest Headlines
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    • Profile photo of OncologyTimes
      OncologyTimes

      A new library documenting mutations can help explain why some #cancers don't respond to #immunotherapies. Researchers from @sangerinstitute used #CRISPR gene editing technology and mini tumors to understand the role of mutations in #bowelcancer cell lines: https://t.co/b2qukYv0Ez https://t.co/p4WOaIRJHy

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    Gene test could guide use of cancer chemotherapy - 2 year(s) ago

    A gene test already used routinely in the NHS can guide use of chemotherapy in people with bowel cancer by predicting whether or not they will benefit.

    Source: www.icr.ac.uk
    Categories: Hem/Onc News and Journals, Latest Headlines
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    • Profile photo of ICR_London
      ICR_London

      A gene test already used routinely in the NHS can guide use of chemotherapy in people with #BowelCancer by predicting whether or not they will benefit. Joint research between the ICR, @imperialcollege, and @NKI_nl. Find out more 👇 https://t.co/9VcGag6rJL https://t.co/nx9439oVfy

  • Mashup Score: 1
    Gene test could guide use of cancer chemotherapy - 2 year(s) ago

    A gene test already used routinely in the NHS can guide use of chemotherapy in people with bowel cancer by predicting whether or not they will benefit.

    Source: www.icr.ac.uk
    Categories: Hem/Onc News and Journals, Latest Headlines
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    • Profile photo of ICR_London
      ICR_London

      🧬NEWS: A gene test already used routinely in the NHS can guide use of #chemotherapy for people with advanced #BowelCancer by predicting whether or not they will benefit. The test offers the prospect of a more #PersonalisedMedicine approach to chemo. https://t.co/75fdk1XZ3a

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    Genes - 2 year(s) ago

    Listen to this episode from Talking With Cancer on Spotify. Katie is feeling like one of the family at the ICR. She was thrilled to speak to another one of their fascinating researchers, Professor Trevor Graham who has moved his lab over from Bart’s, looking at the evolution of cancer genes. He shares his knowledge around how cancer genes evolve and how and why they can become drug resistant. He…

    Source: Spotify
    Categories: Hem/Onc News and Journals, Latest Headlines
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    • Profile photo of ICR_London
      ICR_London

      🎧 On the latest episode of #TalkingWithCancer, Professor @trevoragraham, Director of our Centre for #Evolution and #Cancer (@CEC_ICR), shares more on his work on understanding #CancerEvolution in #BowelCancer. Listen here: https://t.co/qm9lpdezkF https://t.co/GlTGRUHUFj

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