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Mashup Score: 14Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study - 4 year(s) ago
Objective To assess the association between long term prescription opioid treatment medically dispensed for non-cancer pain and the initiation of injection drug use (IDU) among individuals without a history of substance use. Design Retrospective cohort study. Setting Large administrative data source (containing information for about 1.7 million individuals tested for hepatitis C virus or HIV in…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 4Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study - 4 year(s) ago
Objective To assess the association between long term prescription opioid treatment medically dispensed for non-cancer pain and the initiation of injection drug use (IDU) among individuals without a history of substance use. Design Retrospective cohort study. Setting Large administrative data source (containing information for about 1.7 million individuals tested for hepatitis C virus or HIV in…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
What is the association between long term prescription opioid treatment and the initiation of injection drug use? The overall rate of injection drug use initiation was infrequent but still higher than for opioid naive individuals, finds #BMJResearch https://t.co/VAMkovd6WX
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Mashup Score: 8
Objective To review the evidence on the effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality. Design Systematic review and meta-analysis. Data sources Medline, Embase, CINAHL, Biosis, Joanna Briggs, Global Health, and World Health Organization COVID-19 database (preprints). Eligibility criteria for study selection…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
NEW #BMJResearch Several personal protective and social measures, including handwashing, mask wearing, and physical distancing are associated with reductions in the incidence covid-19 and should be continued alongside vaccination https://t.co/Is6EDQTxQB
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Mashup Score: 14Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study - 4 year(s) ago
Objective To determine whether whole genome sequencing can be used to define the molecular basis of suspected mitochondrial disease. Design Cohort study. Setting National Health Service, England, including secondary and tertiary care. Participants 345 patients with suspected mitochondrial disorders recruited to the 100 000 Genomes Project in England between 2015 and 2018. Intervention Short…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Whole genome sequencing is a useful diagnostic test in patients with suspected mitochondrial disorders, yielding a diagnosis in a further 31% after exclusion of common causes, according to new #BMJResearch @cam_mito https://t.co/HdQz9nSGSw
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Mashup Score: 2
When I started as a specialty registrar in clinical genetics in 2013, genetic testing for rare disorders in the NHS involved single gene tests. These were performed at different specialist laboratories, by the labour-intensive process of Sanger sequencing. Due to the financial cost, sequencing was only ordered through clinical genetics departments, and requests were scrutinised at a departmental…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
"We recommend that whole genome sequencing should be used early in the 'diagnostic odyssey,' before invasive tests so that patients can benefit from the power of this new technology." Katherine Schon describes what her team learnt from new #BMJResearch https://t.co/wBTV7zVO8w
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Mashup Score: 25
When I started as a specialty registrar in clinical genetics in 2013, genetic testing for rare disorders in the NHS involved single gene tests. These were performed at different specialist laboratories, by the labour-intensive process of Sanger sequencing. Due to the financial cost, sequencing was only ordered through clinical genetics departments, and requests were scrutinised at a departmental…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
"We recommend that whole genome sequencing should be used early in the 'diagnostic odyssey,' before invasive tests so that patients can benefit from the power of this new technology." Katherine Schon describes what her team learnt from new #BMJResearch https://t.co/RlF7cwPrH1
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Mashup Score: 4Inhaled and intranasal ciclesonide for the treatment of covid-19 in adult outpatients: CONTAIN phase II randomised controlled trial - 4 year(s) ago
Objective To determine if inhaled and intranasal ciclesonide are superior to placebo at decreasing respiratory symptoms in adult outpatients with covid-19. Design Randomised, double blind, placebo controlled trial. Setting Three Canadian provinces (Quebec, Ontario, and British Columbia). Participants 203 adults aged 18 years and older with polymerase chain reaction confirmed covid-19,…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
This placebo controlled randomised trial failed to show statistically significant improvement in symptoms among healthy, young participants with covid-19 presenting with prominent respiratory symptoms #BMJResearch @ezer_nicole https://t.co/9iXbrqDcXs
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Mashup Score: 1Cardioversion in patients with newly diagnosed non-valvular atrial fibrillation: observational study using prospectively collected registry data - 4 year(s) ago
Objective To investigate the clinical outcomes of patients who underwent cardioversion compared with those who did not have cardioverson in a large dataset of patients with recent onset non-valvular atrial fibrillation. Design Observational study using prospectively collected registry data (Global Anticoagulant Registry in the FIELD-AF—GARFIELD-AF). Setting 1317 participating sites in 35…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
A lower risk of mortality was observed in this study for patients with newly diagnosed atrial fibrillation who underwent early cardioversion compared with patients who did not have early cardioversion #BMJResearch by @TRI_Thrombosis https://t.co/NEa59T4ijK
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Mashup Score: 3Cardioversion in patients with newly diagnosed non-valvular atrial fibrillation: observational study using prospectively collected registry data - 4 year(s) ago
Objective To investigate the clinical outcomes of patients who underwent cardioversion compared with those who did not have cardioverson in a large dataset of patients with recent onset non-valvular atrial fibrillation. Design Observational study using prospectively collected registry data (Global Anticoagulant Registry in the FIELD-AF—GARFIELD-AF). Setting 1317 participating sites in 35…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
A lower risk of mortality was observed in this study for patients with newly diagnosed atrial fibrillation who underwent early cardioversion compared with patients who did not have early cardioversion @TRI_Thrombosis #BMJResearch https://t.co/r0QsAAvvdM
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Mashup Score: 6
Objective To examine the risk of urogenital, colorectal, and neurological cancers after a first diagnosis of acute urinary retention. Design Nationwide population based cohort study. Setting All hospitals in Denmark. Participants 75 983 patients aged 50 years or older with a first hospital admission for acute urinary retention during 1995-2017. Main outcome measures Absolute risk of…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
A first diagnosis of acute urinary retention in patients aged 50 years or older was a clinical marker not only for prostate cancer but also for other urogenital cancers and colorectal and neurological cancers, according to new #BMJResearch https://t.co/Xe3cnyXo1O @dceaarhus
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The rate of injection drug use initiation among individuals who received chronic prescription opioid treatment for non-cancer pain was infrequent overall (3-4% within five years), but 8-10 times higher than opioid naive individuals, finds new #BMJResearch https://t.co/cL88DPDnIM