T cell receptor precision editing of regulatory T cells for celiac disease
Regulatory T cells with engineered specificity for HLA-DQ2.5–restricted deamidated gluten peptides exert bystander suppression in vivo.
Regulatory T cells with engineered specificity for HLA-DQ2.5–restricted deamidated gluten peptides exert bystander suppression in vivo.
Nature Nanotechnology – Engineered pyroptotic vesicles formed during tumour cell pyroptosis and engineered as personalized tumour vaccines can activate a robust antitumour immune response for…
The Perspective “Astrocytes, hidden puppet masters of the brain” (15 May 2025, p. 705) stated that Chen et al., authors of one of the related…
Bogong moths fly 1000 kilometers orienting to stars and the Milky Way, an ability never seen before in invertebrates
The brain’s response to injury includes the activation of intrinsic microglia and the influx of leukocytes, collectively constituting neuroinflammation, the “flame” of the brain. Although…
When it comes to research, who speaks for the 19th century workers buried at Maryland’s Catoctin Forge?
Lipid nanoparticles are designed to generate therapeutic T cells inside living animal models
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a public health concern, linked with immune-metabolic dysfunction. While lifestyle and dietary modifications remain the cornerstone of…
PSGL-1 acts as a phagocytosis checkpoint to promote tumor immune escape through impeding LFA-1 activation in macrophages.
Defining viral proteomes is crucial to understanding viral life cycles and immune recognition but the landscape of translated regions remains unknown for most viruses. We…
A study combined long-buried DNA and direct-to-consumer testing to uncover the lineage of free and enslaved African Americans.