Key PointsSurface pre-TCR α chain (pTα) is often expressed in cortical T-ALL and predicts LCK activation.Pre-TCR and IL-7R are aberrantly coexpressed in co
In this issue of Blood, Nguyen et al report that models of germinal center (GC)-derived B-cell lymphoma (BCL) display synthetic vulnerability to combined i
Key PointsBCL11A disruption impairs erythroid precursor expansion in vitro and after xenotransplantation into immunodeficient mice.BCL11A regulates at leas
The Video Journal of Hematological Oncology (VJHemOnc) is a global, open-access video journal, dedicated to providing trusted and up-to-date medical information in order to improve…
Thomas R. Collins is a medical journalist based in West Palm Beach, Florida. The combination of the BTK inhibitor zanubrutinib and the BCL2 inhibitor venetoclax…
Key Points. Biallelic disruption of CD38 is a rare but recurrent phenomenon in anti-CD38 exposed relapsed/refractory multiple myeloma.Mutations in CD38 can
ASTRO holds annual elections for its Board of Directors.
In this issue of Blood, Zaiken et al provide compelling evidence that Tet3 deficiency in donor T cells promotes the differentiation of interleukin-4 (IL-4)
Key PointsRenal impairment and enhanced venous thrombosis in Townes AS mice mimic similar complications in humans with SCT.Nephropathy and increased size o
The Video Journal of Hematological Oncology (VJHemOnc) is a global, open-access video journal, dedicated to providing trusted and up-to-date medical information in order to improve…
