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Mashup Score: 14Ovarian Tissue Collection for Fertility Preservation in Children: The Need for Standardised Surgical Practice Guidance - 6 day(s) ago
Chemotherapy, pelvic radiotherapy (including total body irradiation) and novel compounds used to treat children and teenagers with benign or malignant diseases can lead to impaired fertility. For prepubertal female patients at high risk of treatment-related infertility, upfront storage of ovarian tissue is increasingly being recognised as standard of care. No surgical guidelines exist to ensure best practice technique. We reviewed current UK practice to assess surgical management.
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 14Ovarian Tissue Collection for Fertility Preservation in Children: The Need for Standardised Surgical Practice Guidance - 6 day(s) ago
Chemotherapy, pelvic radiotherapy (including total body irradiation) and novel compounds used to treat children and teenagers with benign or malignant diseases can lead to impaired fertility. For prepubertal female patients at high risk of treatment-related infertility, upfront storage of ovarian tissue is increasingly being recognised as standard of care. No surgical guidelines exist to ensure best practice technique. We reviewed current UK practice to assess surgical management.
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 0
Advances in hepatoblastoma treatment have improved survival but have been accompanied by the chronic toxicities of pediatric cancer therapy. Cisplatin is the cornerstone of chemotherapy treatment for hepatoblastoma. The most frequent long-term complication of hepatoblastoma treatment is cisplatin-related ototoxicity. Among children who receive cisplatin, 25-90% will exhibit measurable hearing loss, impacting language and social development [1]. Therefore, efforts to identify children eligible for reduction or elimination of cisplatin-based chemotherapy while maintaining excellent oncologic outcomes are paramount in reducing the long-term toxicities of hepatoblastoma cancer treatment.
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 33
Minimally invasive surgery (MIS) is gaining traction as a first-line approach to repair congenital anomalies. This study aims to evaluate outcomes for neonates undergoing open versus MIS repairs for esophageal atresia/tracheoesophageal fistula (EA/TEF).
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet-
New infographic by @EmGooteeMD “Association of Operative Approach w/ #Postop Outcomes in Neonates Undergoing #Surgical Repair of #EA #TEF“ Castro P et. al. Full text:https://t.co/QR4Vd2wQuN #pedsurg #SoMe4PedSurg #surgery #Congenital #MIS #Thoracoscopy @jpedsurg @CincyChildrens https://t.co/R6GmGAxfuT
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Mashup Score: 3An enhanced recovery after surgery protocol in children who undergo nephrectomy for Wilms tumor safely shortens hospital stay - 14 day(s) ago
Wilms tumor is the most common malignant solid tumor that arises from the kidneys in children with approximately 500–600 new cases diagnosed yearly in the US. [1,2] Standard treatment includes chemotherapy and sometimes radiation therapy, but the cornerstone of treatment for unilateral tumors remains total nephrectomy and staging laparotomy with retroperitoneal lymph node sampling. While total nephrectomy is considered a major abdominal operation, it is often well tolerated within the pediatric Wilms tumor population and average length of stay continues to decrease, allowing for prompt oncologic follow-up and chemotherapy as recommended by the Children’s Oncology Group (COG) [3,4].
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 9Optimizing Congenital Diaphragmatic Hernia Repair on ECMO: Evaluating the Risk of Bleeding - 15 day(s) ago
Institutions lack consensus on the management of patients with congenital diaphragmatic hernia (CDH) who are repaired on extracorporeal membrane oxygenation (ECMO). Our study aimed to evaluate risk factors associated with bleeding complications in patients with CDH repaired on ECMO.
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 0Children from disadvantaged neighborhoods experience disproportionate injury from interpersonal violence - 16 day(s) ago
Injury is the leading cause of death and disability among children in the United States (US) [1]. A major cause of pediatric injury is violence. The World Health Organization defines violence as “the intentional use of physical force or power, threatened or actual, against oneself, another person, or against a group or community, that either results in or has a high likelihood of resulting in injury, death, psychological harm, maldevelopment or deprivation” [2]. Interpersonal violence is one type of violence, defined as the intentional use of physical force against others by another individual or small group, which results in considerable morbidity and mortality [3].
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 12Anastomotic Leak and its Implications: A Multicenter Analysis of “Type C” Esophageal Atresia / Tracheo-esophageal fistula (EA/TEF) - 20 day(s) ago
Repair of type C esophageal atresia with tracheo-esophageal fistula (EA/TEF) may be complicated by esophageal anastomotic leak. Risk factors associated with leak and the impact of leak on inpatient outcomes remains uncertain. Our objectives are to estimate the associations between clinical factors and esophageal anastomotic leak and quantify the association of leak with length of stay (LOS) in infants who underwent repair of type C EA/TEF.
Source: www.jpedsurg.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 12Sildenafil attenuates intestinal injury in necrotizing enterocolitis independently of endothelial nitric oxide synthase - 21 day(s) ago
Necrotizing enterocolitis (NEC) is a devasting intra-abdominal disease that occurs primarily in preterm neonates. Clinically, NEC presents as feeding intolerance, abdominal distention, and bloody stools, which can quickly progress to sepsis and intestinal perforation [1]. Mortality from NEC remains high and accounts for 10–21% of all deaths in premature babies [2]. Multiple factors have been shown to play a role in its development, including prematurity, formula feeds, and intestinal dysbiosis [3,4].
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
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Mashup Score: 13Modified technique for robot-assisted laparoscopic infantile ureteral reimplantation for obstructive megaureter - 23 day(s) ago
To describe a novel modification of technique to improve efficacy of robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR-EV) in infants.
Source: www.jpedsurg.orgCategories: General Medicine News, PediatricsTweet
New infographic by @EmGooteeMD “#Ovarian Tissue Collection for #Fertility Preservation in Children“ Braungart S et. al. Full text: https://t.co/smv8j4wk6w #pedsurg #SoMe4PedSurg #cryopreservation #oncology @jpedsurg @cincychildrens https://t.co/2CWcCg8uyG