• Mashup Score: 281

    Objective: To describe and evaluate the nature and methodology of reports and appropriateness of conclusions in MMWR pertaining to masks.Background: Because Morbidity and Mortality Weekly Report (MMWR) has substantial influence on United States health policy, it is critical to understand the scientific process within the journal. Mask policies have been highly influenced by data published in the MMWR.Methods: Retrospective cross-sectional study of MMWR publications pertaining to masks from 1978 to 2023.

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    • Nice work @TracyBethHoeg & team. @CDCgov preaches mask efficacy in 77 studies despite only 30% actually testing masks, and fewer than 11 having statistically significant findings. Oh! And no randomized trials 🙄 Can't WAIT to see a changing of the guard! https://t.co/UcMQEqg4QE

  • Mashup Score: 179

    Objective: To describe and evaluate the nature and methodology of reports and appropriateness of conclusions in MMWR pertaining to masks.Background: Because Morbidity and Mortality Weekly Report (MMWR) has substantial influence on United States health policy, it is critical to understand the scientific process within the journal. Mask policies have been highly influenced by data published in the MMWR.Methods: Retrospective cross-sectional study of MMWR publications pertaining to masks from 1978 to 2023.

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    • ALL mask studies in @CDCMMWR Evidence is weak 0% randomized controlled trials 75% concluded "masks work" Despite only 15% being significant CDC does not follow the science, they contribute to low quality science noise @vkprasadlab https://t.co/sh0SunFlF8 https://t.co/Me1lLlz8B2

  • Mashup Score: 145

    On December 22, 2021, the US Food and Drug Administration (FDA) issued emergency use authorization (EUA) for the combination of nirmatrelvir and ritonavir tablets co-packaged and sold by Pfizer (New York, NY) under the name Paxlovid for individuals over the age of 12 years. Data supporting EUA comes from EPIC-HR, a randomized, double-blind, placebo-controlled trial of adult patients with COVID-19 who had one or more risk factors for progression to severe disease (Table).1-3 Crucially, none of the participants had received a COVID-19 vaccine or had a prior documented infection with COVID-19.

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    • We called Paxlovid a regulatory gamble and it looks like it went bust This is am important question https://t.co/Y9Vmr9o5Sa https://t.co/mSpgMEC4wB

  • Mashup Score: 0

    At the time of this writing, the reality of mortality remains as unshakeable as ever. Although the field of regenerative medicine witnessed substantial gains owing to the likes of Juan Carlos Izpisua-Belmonte, Ph.D. and David A. Sinclair, A.O, Ph.D., the best one can hope for, at present, is a modest extension of life expectancy.1,2 Far greater uncertainty pervades the highly speculative, if ever present prospect of human cloning as a means of securing post-mortem “immortality.”3 It would thus appear that for the foreseeable future, the biblical admonition of Adam – “for you are dust, and to dust you shall return” – is holding firm with no obvious, let alone near-term relief in sight.

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    • 1 “...the rest of us have been gone for a thousand years. If you remember what we were, and how we lived, then we'll have found life again.” The Anguish of Mortality and the Burden of Remembrance - The American Journal of Medicine https://t.co/HsRLasUjZ8

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    Several common misconceptions can make the clinical diagnosis of subacute pericardial tamponade challenging. Widely known physical findings of pericardial tamponade lack sensitivity and specificity. Interpretation of echocardiographic signs requires good understanding of pathophysiology. Over-reliance on echocardiography may result in over-utilization of pericardial drainage procedures. Awareness of these misconceptions with an integrative approach to both clinical and imaging data will help clinicians to assess the hemodynamic impact of pericardial effusion and the need for drainage.

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    • @DavidLBrownMD @EM_RESUS Indeed, one can be hypertensive and have tamponade - ventricular interdepence and impaired cardiac filling. And don't "precautionarily" intubate patients. Inspiratory RA filling, what little there is - is crucial. Oft cited refetence to fellows: https://t.co/Be6JfguZAz

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    ReviewsAdvancing high value health careDiagnostic dilemmaECG image of the monthImages in radiologyClinical research studiesAJM onlineDiagnostic dilemmaClinical communications to the EditorLettersThe ReplyChayakrit Krittanawong,Bharat Narasimhan,Zhen Wang,…Ann M. Farrell,HongJu Zhang,WH Wilson TangPublished in issue: October 2021e532Full-Text HTMLPDF The ReplyTodd C. Lee,Marnie…

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    • I was so excited when I opened the October issue of @amjmed. So many exciting and important articles from friends and colleagues. Here are a few I'd like to highlight! https://t.co/ibH2oJ5Emz

  • Mashup Score: 10

    Julio Núñez, Pau LlĂ cer, Sergio GarcĂ­a-Blas, Clara Bonanad, Silvia Ventura, JosĂ© MarĂ­a Núñez, Ruth Sánchez, Lorenzo Fácila, Rafael de la Espriella, Juana MarĂ­a Vaquer, Alberto Cordero, Mercè RoquĂ©, Carlos Chamorro, Vicent Bodi, Ernesto Valero, Enrique Santas, MarĂ­a del Carmen Moreno, Gema Miñana, Arturo Carratalá, Enrique RodrĂ­guez, Anna Mollar, Patricia Palau, MarĂ­a JosĂ© Bosch, Vicente…

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    • RT @fischman_david: Why Are Women Underrepresented in Cardiology. Some thoughts⬇️ What are yours? https://t.co/EtsCGdXpLH @DrMarthaGulati @…

  • Mashup Score: 3

    Julio Núñez, Pau LlĂ cer, Sergio GarcĂ­a-Blas, Clara Bonanad, Silvia Ventura, JosĂ© MarĂ­a Núñez, Ruth Sánchez, Lorenzo Fácila, Rafael de la Espriella, Juana MarĂ­a Vaquer, Alberto Cordero, Mercè RoquĂ©, Carlos Chamorro, Vicent Bodi, Ernesto Valero, Enrique Santas, MarĂ­a del Carmen Moreno, Gema Miñana, Arturo Carratalá, Enrique RodrĂ­guez, Anna Mollar, Patricia Palau, MarĂ­a JosĂ© Bosch, Vicente…

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    • Why Are Women Underrepresented in Cardiology. Some thoughts⬇️ What are yours? https://t.co/EtsCGdXpLH @DrMarthaGulati @MinnowWalsh @JGrapsa @mirvatalasnag @hvanspall @AnastasiaSMihai @DrFerNunez @purviparwani @saraceciliamtz @Pooh_Velagapudi @mmamas1973 @HeartBobH #cardiotwitter https://t.co/8jvhl7kOOi