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Mashup Score: 0Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus - 5 year(s) ago
HIV-1 reverse transcription is found to be completed in the nucleus of the cell using an HIV-1 nuclear import kinetic assay that takes advantage of a nuclear import blockade method to monitor the kinetics of HIV-1 entry and infection.
Source: Nature MicrobiologyCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 3Phylogenetic interpretation during outbreaks requires caution - 5 year(s) ago
How viruses are related, and how they have evolved and spread over time, can be investigated using phylogenetics. Here, we set out how genomic analyses should be used during an epidemic and propose that phylogenetic insights from the early stages of an outbreak should heed all of the available epidemiological information.
Source: Nature MicrobiologyCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
A @NatureMicrobiol Comment article argues how genomic analyses should be used during an epidemic and proposes that phylogenetic insights from the early stages of an outbreak should heed all of the available epidemiological information. https://t.co/Hmc3p0Onrk https://t.co/CiTSGwQFct
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Mashup Score: 2SARS-CoV-2 detection in patients with influenza-like illness - 5 year(s) ago
Here, it is shown that there was community transmission of SARS-CoV-2 early in January.
Source: Nature MicrobiologyCategories: General Medicine Journals and SocietiesTweet-
Findings in @NatureMicrobiol suggest that community transmission of SARS-CoV-2 was established in early January in Wuhan, China. The study re-analysed throat swabs collected from October 6 to January 21 from patients who had influenza-like illness. https://t.co/mo1b8sd5qR https://t.co/vYHM6lUzLJ
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Mashup Score: 6Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth - 5 year(s) ago
The murine gut commensal Faecalibaculum rodentium and its human homologue, Holdemanella biformis, are under-represented in tumour development and can reduce tumour progression via short-chain fatty acid production, providing insights into a protective microbial candidate.
Source: Nature MicrobiologyCategories: Healthcare ProfessionalsTweet-
@nature @HansClevers @Cayetanopm @_Hubrecht Such an important smoking gun for the gut #microbiome's potential contribution to cancer, just as we've recently seen it's ability to protect from cancer https://t.co/AZf1nPW4tU @NatureMicrobiol https://t.co/UXRd3GcgIj
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Mashup Score: 0The microbiota programs DNA methylation to control intestinal homeostasis and inflammation - 5 year(s) ago
A comparison of DNA methylation patterns between conventionally raised and germ-free mice shows that the presence of a commensal microbiota induces methylation changes at regulatory elements in a subset of genes that are important for intestinal homeostasis.
Source: Nature MicrobiologyCategories: GastroenterologyTweet-
#GastroEdPick Exposure to commensal microbiota induced methylation changes at regulatory elements, activating genes important for intestinal homeostasis, in conventionally raised (compared with germ-free) mice. #gutmicrobiome @NatureMicrobiol https://t.co/HjLvLNFVqG
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Mashup Score: 0Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth - 5 year(s) ago
The murine gut commensal Faecalibaculum rodentium and its human homologue, Holdemanella biformis, are under-represented in tumour development and can reduce tumour progression via short-chain fatty acid production, providing insights into a protective microbial candidate.
Source: Nature MicrobiologyCategories: GastroenterologyTweet-
#GastroEdPick A new study identifies two anti-tumorigenic strains of bacteria - one in mice and a human homologue. Both are lost in early tumorigenesis and block tumour growth by reducing activation of NFATc3 and calcineurin. #coloncancer @NatureMicrobiol https://t.co/gSFzBFLLdC
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Mashup Score: 5Culture-enriched metagenomic sequencing enables in-depth profiling of the cystic fibrosis lung microbiota - 5 year(s) ago
The PLate Coverage Algorithm (PLCA) determines the culture plates required for culture-enriched metagenomics and enables the recovery of greater taxonomic diversity, better quality metagenome-assembled genomes and improved functional annotations compared to metagenomics alone, indicating its utility for other microbiomes, especially those dominated by host DNA.
Source: Nature MicrobiologyCategories: Future of MedicineTweet-
Combining cultivation with metagenomics AKA culture-enabled metagenomics improves our understanding of sparse microbiomes in human cystic fibrosis sputum samples, and could prove broadly applicable #NBTHighlight https://t.co/aEm2mFGEpH
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Mashup Score: 12Tracking microbial evolution in the human gut using Hi-C reveals extensive horizontal gene transfer, persistence and adaptation - 6 year(s) ago
High-throughput chromosomal conformation capture identified changes in the gut microbiome over 10 years, including substantial exchange of accessory elements and adaptive evolution in core genomes.
Source: Nature MicrobiologyCategories: Healthcare ProfessionalsTweet-
Our gut #microbiome undergoes dynamic evolution: #metagenomic sequencing shows plenty of horizontal gene transfer between microbes and accessory elements https://t.co/44fU78OxYL @NatureMicrobiol by @EitanYaffe @DavidRelman @StanfordMed (our inner diversity driving uniqueness) https://t.co/8MdEuBspnL
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A team of researchers from Loyola University Chicago (@LoyolaChicago), led by Edward Campbell, define the spatio-temporal staging of critical steps of #HIV-1 infection. https://t.co/xHj7ZU6WQG https://t.co/STQ49Poyt7