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Mashup Score: 1Cytoreductive Surgery in Patients with Urothelial Bladder Cancer - 2 year(s) ago
Cytoreductive cystectomy appears to have survival advantages as a part of multimodal approach for well-selected patients with bladder cancer. Patient with clinical lymph node metastases might benefit from surgical consolidation after achieving a measurable response to chemotherapy. The exact role of cytoreductive/consolidative cystectomy is yet to be determined in well-designed prospective trials.
Source: European Urology FocusCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 6Ureteral Obstruction Promotes Ureteral Inflammation and Fibrosis - 2 year(s) ago
Ureteral obstruction causes an acute inflammatory response mediated by T cells, Th1 cells, and M1 macrophages; with prolonged obstruction, the ureter undergoes fibrotic changes.Ureteral obstruction might impair ureteral functionality in the long term due to fibrosis.The contralateral ureter might be affected.
Source: European Urology FocusCategories: Latest Headlines, UrologyTweet
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Mashup Score: 1
Genomic profiling represents the first clinical practice–ready tool for precision oncology in metastatic prostate cancer. Here we outline current testing considerations and gray zones regarding how best to apply genomic testing in the clinic. The lessons we learn today will continue to shape how we integrate evolving biology and future technologies into practice.
Source: European Urology FocusCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 0
Our study evaluated changes in microbiome after circumcision in children. The findings highlighted by our analysis show a remarkable change in overall bacterial and fungal compositions, and a shift from anaerobic to aerobic bacteria and skin flora. The reduction in bacterial and fungal bioburden seen in our study may correlate with a potential inflammatory cascade and oncogenic processes seen in…
Source: European Urology FocusCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2
Our paper is the first to analyze female editorial/leadership representation at >100 urology journals by role position. Overall, females are six times less likely to hold leadership positions, and are more likely to have nonacademic and/or administrative roles.
Source: European Urology FocusCategories: Latest Headlines, UrologyTweet
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Mashup Score: 6
This is the largest series looking at the association between Decipher and unfavorable pathologic features in prostate cancer.Molecular subtyping and gene set enrichment identified candidate pathways that might drive the pathogenesis of these outcomes.
Source: European Urology FocusCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 3
This is the largest series looking at the association between Decipher and unfavorable pathologic features in prostate cancer.Molecular subtyping and gene set enrichment identified candidate pathways that might drive the pathogenesis of these outcomes.
Source: European Urology FocusCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 16Myogenic Underactive Bladder and Heart Failure Resemblance: A Novel Role for SGLT2 Inhibition? - 2 year(s) ago
The heart and the bladder share biomechanical determinants of muscle function. Heart failure and myogenic underactive bladder share pathophysiological mechanisms. Groundbreaking drugs in heart failure, namely SGLT2 inhibitors, could also be promising for myogenic underactive bladder.
Source: European Urology FocusCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 4
In multiple areas of urologic disease we are finally entering the era of precision medicine, personalizing management strategies based on an understanding of an individual patient’s biology rather than simply on a diagnosis. Application of these insights in clinical practice is typically achieved through biomarkers, indicators of disease or host status that are readily measurable in blood, urine,…
Source: European Urology FocusCategories: Latest Headlines, Oncologists1Tweet
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Mashup Score: 1
Multiple urine-, blood-, and tissue-based biomarkers are commercially available for detection and risk stratification of prostate cancer. In general, while promising, they should still be used with caution and major guidelines are largely discordant on their use.
Source: European Urology FocusCategories: Hem/Oncs, Latest HeadlinesTweet
RT @EurUrolFocus: Highlight: Cytoreductive Surgery in Patients with Urothelial Bladder Cancer https://t.co/YHCwAYZgAq @MAbufaraj @Uroge…