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Mashup Score: 1The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice - 3 year(s) ago
The FDA-approved rheumatoid arthritis drug auranofin accumulates in white adipose tissue, improves insulin sensitivity, and normalizes fatty-liver disease in obesity. Beta-adrenergic receptor regulation of leptin secretion generates metabolic benefits superior to anti-inflammatory effects. Consequently, studies of auranofin reinforce that partial leptin reduction represents a relevant method for…
Source: Cell MetabolismCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 91
Diet influences intestinal microbiota, inflammation, and metabolism. Kawano et al. show that dietary sugar engaged upper gut innate lymphoid cells to replace segmented filamentous bacteria with a pathobiont. Added sugar worsened early metabolic disease by lowering protective Th17 immunity, thereby promoting intestinal lipid absorption and obesity in high-fat-diet-fed mice.
Source: Cell MetabolismCategories: Cardiologists, Latest HeadlinesTweet-
RT @Cell_Metabolism: Dietary sugar lowers immunity and microbiota that protect against metabolic disease https://t.co/gnHNjeAaZo https://t.…
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Mashup Score: 4Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial - 3 year(s) ago
Time-restricted eating (TRE) and high-intensity interval training (HIIT) can improve cardiometabolic health, but whether combining these interventions induces superior metabolic improvements over each intervention alone is not known. In a randomized controlled trial, women with overweight/obesity completed 7 weeks of TRE, HIIT, or a combination (TREHIIT). Haganes et al. report that TRE, HIIT, and…
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet-
In women, combining time-restricted eating (#TRE) and high interval training (#HIIIT) reduces fat tissue twice as much compared to when doing either activity alone. @NTNUnorway Kamilla Haganes, @trinemoholdt Read more in @Cell_Metabolism: https://t.co/9i3ESY4j9D
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Mashup Score: 3
Tilg et al. discuss experimental and clinical aspects of the bidirectional gut-liver crosstalk in health and how perturbation of such inter-organ communication promotes liver diseases. Collectively, the diet, gut mucosal immunity and related microbial commensalism, and hepatic metabolism shape the communication along the gut-liver axis, fueling various liver diseases.
Source: Cell MetabolismCategories: Healthcare Professionals, Latest HeadlinesTweet-
RT @DanielJDrucker: Will one be able to successfully target the gut liver axis in humans? @Cell_Metabolism https://t.co/a6TFuvnUXU
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Mashup Score: 0Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial - 3 year(s) ago
Manoogian et al. assessed time-restricted eating (TRE) as a potential lifestyle intervention to improve the health of 24-h shift workers. TRE was feasible and led to improvements in quality of life and cardiometabolic health, especially among participants with abnormal cardiometabolic measures at baseline.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet-
Time restricted eating (#TRE) reduces cardiovascular risk in #firefighters and possibly other 24-hour shift workers. @PamTaubMD, @SatchinPanda Read more in @Cell_Metabolism: https://t.co/42IO8n9MHe
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Mashup Score: 6Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial - 3 year(s) ago
Time-restricted eating (TRE) and high-intensity interval training (HIIT) can improve cardiometabolic health, but whether combining these interventions induces superior metabolic improvements over each intervention alone is not known. In a randomized controlled trial, women with overweight/obesity completed 7 weeks of TRE, HIIT, or a combination (TREHIIT). Haganes et al. report that TRE, HIIT, and…
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet-
In women, combining time-restricted eating (#TRE) and high interval training (#HIIIT) reduces fat tissue twice as much compared to when doing either activity alone. @NTNUnorway Kamilla Haganes, @trinemoholdt Read more in @Cell_Metabolism: https://t.co/9i3ESY4j9D
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Mashup Score: 2
Herrera Moro Chao et al. show that obesity promotes anatomically restricted remodeling of hypothalamic astrocyte activity. In the paraventricular nucleus of the hypothalamus (PVN), chemogenetic manipulation of astrocytes results in bidirectional control of neighboring neuron activity, autonomic outflow, glucose metabolism, and energy balance through the control of ambient glutamate levels.
Source: Cell MetabolismCategories: Endocrinology, Latest HeadlinesTweet-
Hypothalamic astrocytes control systemic glucose metabolism and energy balance https://t.co/amfUE0L10l
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Mashup Score: 1Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial - 3 year(s) ago
Manoogian et al. assessed time-restricted eating (TRE) as a potential lifestyle intervention to improve the health of 24-h shift workers. TRE was feasible and led to improvements in quality of life and cardiometabolic health, especially among participants with abnormal cardiometabolic measures at baseline.
Source: Cell MetabolismCategories: Cardiologists, Latest HeadlinesTweet-
Our study which is the first randomized controlled trial of time restricted eating (TRE) in shift workers (firefighters working 24-hour shifts) was published today in Cell Metabolism and featured on the cover. https://t.co/RY4uIj3a1o🧵 @ASPCardio @ACCinTouch @AHAScience @CMHC_CME https://t.co/evQfTdyKsV
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Mashup Score: 16Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial - 3 year(s) ago
Manoogian et al. assessed time-restricted eating (TRE) as a potential lifestyle intervention to improve the health of 24-h shift workers. TRE was feasible and led to improvements in quality of life and cardiometabolic health, especially among participants with abnormal cardiometabolic measures at baseline.
Source: Cell MetabolismCategories: General Medicine News, Latest HeadlinesTweet-
Time restricted eating (#TRE) reduces cardiovascular risk in #firefighters and possibly other 24-hour shift workers. @PamTaubMD, @SatchinPanda Read more in @Cell_Metabolism: https://t.co/42IO8n9MHe
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Mashup Score: 2Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood - 3 year(s) ago
Borcherding et al. demonstrate that dietary long-chain fatty acids inhibit intercellular mitochondria transfer from adipocytes to macrophages in white adipose tissue. Inhibiting mitochondria capture by macrophages diverts adipocyte-derived mitochondria into the blood for systemic distribution to distant organs, such as the heart.
Source: Cell MetabolismCategories: Endocrinology, Latest HeadlinesTweet-
The original paper in Cell Metabolism -> https://t.co/jWiGeB9trV
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Researchers have long attempted to find a drug that lowers #leptin. Have they found one? The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice: Cell Metabolism #obesity #weight #weightloss https://t.co/qhouF3GlDK