Safety and Sample Adequacy for Comprehensive Biomarker Testing of Bronchoscopic Biopsies: An American Association of Bronchology and Interventional Pulmonology (AABIP) and International Association for the Study of Lung Cancer (IASLC) Clinical Practice Guideline
Linear endobronchial (EBUS) guided sampling of accessible mediastinal lesions is well established as a first-choice modality for lung cancer mediastinal staging. Parenchymal lung lesions, however, are routinely accessed by either a percutaneous (CT-guided) or a bronchoscopic approach. Direct comparisons between the percutaneous approach and bronchoscopy, or EBUS and mediastinoscopy are sparse in regard to diagnostic accuracy and it remains unknown which sampling technique is the safest and offers the most adequate material for comprehensive biomarker testing.
