Chagas disease, caused by the parasite Trypanosoma cruzi, is the neglected tropical disease with the highest burden in Latin America. Now, researchers report in PLOS Neglected Tropical Diseases that two commercially-available rapid diagnostic tests (RDTs) can be combined for conclusive diagnosis of Chagas disease.
Nature Immunology – Stunnenberg et al. use a model of lipopolysaccharide injection in humans to characterize the transcriptomic landscape of bone marrow and blood immune…
Nature Human Behaviour – How does the brain encode complex movement sequences? Qi et al. reveal that the brain decomposes sequences into temporal states, each…
Hexosamine synthesis pathway and SCAP/SREBP-1 reciprocally enhance each other to drive malignant brain tumor growth.
A global study by experts at the University of Sydney has shown that countries that consume more plant-based proteins—such as chickpeas, tofu and peas—have longer…
Translational Psychiatry – Healthy sleep patterns and risk of hospitalization for infection: a large community-based cohort study
Nature Communications – Here, the authors characterize the epigenetic status of hybrid ecDNA in HPVOPC, identifying HPV oncogenes E6/E7 in hybrid ecDNA are flanked by…
This cross-sectional study analyzes the use of 10 no-cost preventive services by individuals with employer-sponsored health insurance, which may be threatened by the upcoming Kennedy…
Annals of Biomedical Engineering – High-frequency irreversible electroporation (H-FIRE) is a minimally invasive local ablation therapy known to activate the adaptive immune system and reprogram…
Hypertension Research – Clinical studies in Myxomatous Mitral Valve Disease dogs: most prescribed ACEI inhibits ACE2 enzyme activity and ARB increases AngII pool in plasma
Original Article from The New England Journal of Medicine — Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer
