Randomized Comparison of a Gladius First vs Standard Antegrade Wiring Strategy for Crossing Coronary Chronic Total Occlusions: The Gladius First Trial

The authors performed a 2-arm randomized controlled trial to compare the time, efficacy and safety outcomes between an antegrade wiring (AW) strategy using a first-choice intermediate tip-load polymer-jacketed guidewire vs an AW strategy using the standard guidewire escalation strategy.

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