Nature Reviews Genetics – Barbadilla-Martínez et al. review recent progress in deep-learning-based sequence-to-expression models, which predict gene expression levels solely from DNA sequence….
Nature Communications – While switch-like expression (“on” in some individuals and “off” in others) has been linked to biological variation and disease susceptibility, a…
Nature – Analysis of species distribution models in a pan-African database comprising chronometrically dated archaeological sites over the past 120,000 years shows major expansion in the…
Nature Genetics – Polygenic risk scores for Alzheimer’s disease derived from individuals of European ancestry can show improved performance in multiancestry settings after incorporating…
Nature – Computer approach creates synthetic enzymes 100 times more efficient than those designed by AI.
Nature Reviews Gastroenterology & Hepatology – This Perspective article provides a detailed overview of the oesophagus as an immune organ, highlighting its innate immune components…
Nature Reviews Clinical Oncology – Zanidatamab shows promise as first-line therapy for advanced-stage HER2+ GEA
Blood Cancer Journal – Guidelines for the testing and reporting of cytogenetic results for risk stratification of multiple myeloma: a report of the Cancer Genomics…
Nature Neuroscience – Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far…
Nature Reviews Neurology – Absence of Lewy body pathology in the form of Parkinson disease caused by mutations in the LRRK2 gene does not equate…
Nature Reviews Neurology – This Review considers how DNA methylation-based biomarkers can be used to monitor brain ageing and stratify neurological disease risk. The authors…
