Podcast Extra: Epigenetics
Hear the biggest stories from the world of science.
Hear the biggest stories from the world of science.
Nature Reviews Drug Discovery – Discover the world’s best science and medicine | Nature.com
Wang et al. show that a ferroptosis signature is compromised in adipose tissues of humans and mice with obesity. By constraining HIF1α availability, ferroptotic signaling in…
npj Drug Discovery – Discovery of a small molecule secreted clusterin enhancer that improves memory in Alzheimer’s disease mice
Nature – An innovative method enables analysis of the clonal lineage of individual cells, without genetic engineering.
Nature – The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone,…
Nature – PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver…
Nature – A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may…
Nature Reviews Molecular Cell Biology – The electron transfer chain in chloroplast thylakoid membranes uses solar energy to produce NADPH and ATP, which power carbon…
Nature Biotechnology – A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.
Nature Reviews Cancer – Reply to ‘Heterogeneity of TP53 mutations necessitates differentiation with p53-rescue therapies’