Goals and Vision of the ProgramAngina predicts outcomes from coronary artery disease, including mortality, morbidity, reduced quality of life, and increased healthcare spending.1 However, patient symptoms are underreported and incompletely documented, limiting understanding of the efficacy of therapies.2 Angina can be reliably assessed using patient-reported outcomes measures (PROMs): short,…
The May issue of Hypertension is dedicated to primary research articles on hypertensive disorders of pregnancy, including gestational hypertension and preeclampsia, in honor of May…
BACKGROUND: To study the risk of incident dementia after a nontraumatic intracranial hemorrhage in a diverse US population and evaluate whether this risk is different…
BACKGROUND: Prior studies on the clinical impact of intracerebral hemorrhage (ICH) location have used visual localization of hematomas to neuroanatomical structures. However, hematomas often cross…
BACKGROUND: There are limited data on ultra-early hematoma growth dynamics and their clinical impact in primary intracerebral hemorrhage (ICH). We aimed to estimate the incidence…
BACKGROUND: Atrial fibrillation detected after stroke (AFDAS) affects secondary stroke prevention, yet identification can be challenging. Easily accessible cardiac blood biomarkers such as NT-proBNP (N-terminal…
Manna et al. addressed the unmet need of cerebroprotective mechanisms in acute ischemic stroke and traumatic brain injury. A phase I trial of AST-004, a…
BACKGROUND: Preeclampsia is a hypertensive pregnancy disorder marked by endothelial damage. Healthy endothelium is covered by a protective glycocalyx layer, which, when degraded, releases detectable…
BACKGROUND: Hemorrhagic infarction (HI) of acute ischemic stroke is frequent. Whether radiologically detected HI affects stroke outcomes has been less explored. METHODS: This was a…
Secondary stroke prevention encompasses many approaches, including antithrombotic therapy, risk factor management, and a healthy lifestyle. Recommendations are typically based on the results of randomized…
BACKGROUND: Stroke often results in significant impairments across various domains, including movement, language, cognition, and mood. Neurostimulants have been proposed as potential therapeutic interventions to…
