Key Points. Prior exposure to CPI is associated with increased PFS due to decreased incidence of relapse after HCT, suggesting an increased GVL.PTCy based
Key PointsPatients with TP53-mutated AML/MDS represent a unique and heterogeneous high-risk group that should not be treated as 1 single entity.Transplant
Key PointsEarly use of daratumumab combinations in patients with MM admitted with kidney injury rapidly reduces sFLCs.Early initiation of daratumumab combi
There is increasing evidence that deep vein thrombosis (DVT) is an inflammation-driven process involving endothelial cells, neutrophils, and platelets. Met
Key PointsFrequent noncoding mutations and loss of expression of BCL7A in MM cells suggest its role as a tumor suppressor in MM.BCL7A binds to IRF4,…
Key PointsHbSC disease is the second most common form of SCD, which has largely been excluded from research and therapies.We developed humanized HbSC mice
In this issue of Blood, Chakraborty et al1 uncover a novel mechanism of control of the transcription factor IRF4. They show that BCL7A can act…
In this issue of Blood, Yin et al1 shed further light on potentially pathogenic mechanisms in idiopathic multicentric Castleman disease (iMCD).
In this issue of Blood, Perrot et al1 reported preliminary results of the MIDAS study showing that roughly two-thirds of patients with newly diagnosed mult
Key PointsEarly use of daratumumab combinations in patients with MM admitted with kidney injury rapidly reduces sFLCs.Early initiation of daratumumab combi
Wiskott-Aldrich syndrome (WAS) is a rare X-linked disorder with highly variable clinical presentation. In this How I Treat article, Vallée and coauthors pr
