At least one in five cases of infertility remain unexplained. Male factors contribute to about half of these cases and, much of the time, men lack a specific causal diagnosis for their infertility. Researchers estimate that genetics could explain up to 50 percent of these cases, but many of the genes involved in male infertility remain unknown. A new study led by investigators at Brigham and…
This cluster randomized clinical trial evaluated if a reduced-sodium, added-potassium salt substitute compared with regular salt decreases the risk of stroke recurrence and death in…
Scientific Reports – Unique events improve episodic richness, enhance mood, and alter the perception of time during isolation
Protein therapeutics such as antibodies require in-depth in vivo characterization during development and consequently account for a large proportio…
One of the most enduring questions humans have is how long we’re going to live. With this comes the question of how much of our…
One of Australia’s most common gynecological cancers could be detected sooner and more accurately thanks to a specialized artificial intelligence (AI) model, new research shows.
This cross-sectional study describes Medicaid managed care plans’ coverage and management of acamprosate, naltrexone, and disulfiram for alcohol use disorder and examines associations of plan…
Nature Microbiology – The FDA-approved antiviral baloxavir improves disease outcomes in mice compared with oseltamivir after ocular and intranasal challenge with A(H5N1)-contaminated cow milk.
A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.
Background Glioblastoma (GBM) is an aggressive brain tumor driven by glioblastoma stem cells (GSCs), which represent an appealing target for therapeutic interventions. The cellular prion…
Nature Communications – Extracellular mRNAs are found to play an important role in premetastatic organs. Here this group reports the non-vesicular extracellular IL1β-mRNA complexes binding…
