Natural peptidoglycan nanoparticles enable rapid antigen purification and potent delivery of plant-derived vaccines
This study reports the development of natural peptidoglycan nanoparticles (NPNs), derived from bacterium-like particles of lactic acid bacteria, as a novel tool for plant-based vaccine purification and delivery. NPNs streamline the purification of recombinant proteins from plant lysates while simultaneously serving as a biodegradable vaccine carrier. This dual functionality both reduces production costs and significantly enhances the resulting immune responses.