The immune system provides essential protection from microbial infection but can damage tissue when its functions are excessive, sustained, or insufficiently regulated. In autoimmune disease, T lymphocytes and autoantibodies (antibodies directed to “self”-antigens) target the immune response to host tissue. But innate immunity, the first response to infection or cell stress, is also important in…
Noninvasive mutation-based and fragmentation-based cfDNA approaches can identify response to therapy in pancreatic cancer.
A St. Louis doctor is investigating the high rates of cancer among younger patients in the region, and is using a multi-cancer early detection screening…
Nature – An innovative method enables analysis of the clonal lineage of individual cells, without genetic engineering.
Nature – The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone,…
Diet can impact anticancer drug activity. A classic example in rodents is a ketogenic diet enhancing PI3K inhibitor activity. Here, we show that phytochemicals and…
A team of scientists has harnessed CRISPR technology to identify a protein that helps cancers spread to bone tissue, opening the do | A team…
Noninvasive mutation-based and fragmentation-based cfDNA approaches can identify response to therapy in pancreatic cancer.
Virginia Rep. Gerry Connolly said his esophageal cancer diagnosis came as a ‘surprise’ in late 2024, six months before his death on May 21
Nature – PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver…
The pause of billions of dollars in research funding to universities has had devastating effects on cancer research as lab work is put on hold…
