Loss-of-function mutations in APOC3, Triglycerides, and Coronary Disease – Kathiresan Lab
Crosby J*, Peloso GM,* Auer PL*, TG and HDL Working Group of the Exome Sequencing Project, National, Heart, Lung, and Blood Institute, Reiner AP*, Boerwinkle E*, Kathiresan S*. In a large-scale population-based exome sequencing study for plasma lipids, we discovered that people who carry rare mutations that reduce the production of the APOC3 protein have …