Longitudinal Changes in Cerebrospinal Fluid tTau and pTau181 and Brain Atrophy in Patients With Alzheimer Disease
This cohort study of participants with dominantly inherited Alzheimer disease examines the rates of change in cerebrospinal fluid levels of total tau (tTau) and phosphorylated tau 181 (pTau181) across the disease course and how the rates of change are associated with brain atrophy.