Linking CRISPR–Cas9 double-strand break profiles to gene editing precision with BreakTag
Nature Biotechnology – The genome-wide landscape of Cas-induced double-strand breaks and end structures is profiled at nucleotide resolution.
Nature Biotechnology – The genome-wide landscape of Cas-induced double-strand breaks and end structures is profiled at nucleotide resolution.
Nature Communications – Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by rapid motor neuron (MN) degeneration, with unclear causes in sporadic cases. Here,…
Ethics experts raise concerns over consent, study design
npj Digital Medicine – Despite significant advances, the prevention and management of cardiovascular disease remain challenging, especially for ischemic heart disease (IHD). Current clinical…
Agency plans to promote alternative methods and address “bias” toward animal studies in grant review
I was sitting with my son on a step leading up to the Lincoln Memorial in Washington, DC, which, on this sunny March afternoon, also…
Scientific Reports – Adolescent marriage, maternity, and limited access to education in 106 countries: Bayesian analysis of prevalence, trend, and prediction
As AI agents become more prevalent and powerful, a new paper outlines a framework for better-understanding how to govern and regulate them.
Aerial AM, using aerial robots for scalable, agile construction, will need to overcome challenges to unlock its full potential.
Experimental & Molecular Medicine – Periodontitis is a gum disease that damages the tissues and bones supporting teeth. The study explores how Porphyromonas gingivalis worsens…
Assessing a full range of environmental exposures will improve human health