JACC: Case Reports
View the JACC: Case Reports landing page, presenting the most recent and relevant articles on cardiovascular case reports.
Related Articles
The Global Syndemic of Modifiable Cardiovascular Risk Factors Projected From 2025 to 2050:
AbstractBackgroundCardiovascular diseases (CVDs) are the leading cause of global mortality. Understanding epidemiologic trends in the modifiable risk factors driving CVDs is essential in designing …
A Case of Postural Orthostatic Tachycardia Syndrome in a 20-Year-Old Female Athlete: Review of Ivabradine Guidelines
AbstractBackgroundPostural orthostatic tachycardia syndrome (POTS) is a disorder characterized by orthostatic intolerance, tachycardia, and syncope. Ivabradine, though not Food and Drug Administrat…
JACC: Case Reports
View the JACC: Case Reports landing page, presenting the most recent and relevant articles on cardiovascular case reports.
Transcatheter Tricuspid Valve Replacement After Failed Transcatheter Annuloplasty and Edge-to-Edge Repair:
AbstractBackgroundThe EVOQUE transcatheter tricuspid heart valve (Edwards Lifesciences) is approved for high-risk patients with severe tricuspid regurgitation (TR). This report describes the first …
Outcomes of Lesions With Discordance Between FFR and Nonhyperemic Pressure Ratios:
AbstractBackgroundDiscordance between fractional flow reserve (FFR) and nonhyperemic pressure ratios (NHPRs) can occur in about 20% of clinical cases, creating treatment dilemmas in the cardiac…
Interleukin-6 in Heart Failure With Reduced Ejection Fraction and the Effect of Dapagliflozin: An Exploratory Analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure Trial
AbstractBackgroundInflammation may play an important pathophysiological role in the development and progression of heart failure (HF). Interleukin (IL)-6 is a circulating cytokine and is the…
At the Prevention Tipping Point:
∗Address for correspondence: Dr Harlan M. Krumholz, Editor-in-Chief, JACC, Yale School of Medicine, 195 Church Street, Fifth Floor, New Haven, Connecticut 06510, USA. E-mail: E-mail…
Sealing the Threat: Life-Saving Percutaneous Device Closure of Rare Left Ventricular Pseudoaneurysm Following Myocardial Infarction:
AbstractBackgroundLeft ventricular pseudoaneurysm (LVPA) is a rare yet potentially life-threatening complication following myocardial infarction or cardiac surgery. Although surgical repair has tra…
The Global Syndemic of Modifiable Cardiovascular Risk Factors Projected From 2025 to 2050:
AbstractBackgroundCardiovascular diseases (CVDs) are the leading cause of global mortality. Understanding epidemiologic trends in the modifiable risk factors driving CVDs is essential in designing …
NLRP3 Inflammasome Inhibition by the Novel Bispecific Antibody InflamAb Attenuates Atherosclerosis in Apolipoprotein E–Deficient Mice:
Highlights •We developed a novel bispecific antibody, InflamAb, designed to target the IL-1R1 for cell entrance and inhibit the intracellular NLRP3 inflammasome.•InflamAb potently inhibits NLRP3…