Polygenic risk scores (PRSs) capture the polygenic architecture of common diseases by aggregating genome-wide genetic variation into a single score that reflects individual’s disease risk, affording a new opportunity to identify downstream molecular pathways involved in disease pathogenesis. We performed an integrative analysis to characterise associations of PRSs of five cardiometabolic diseases…
Hype around a Microsoft AI agent’s ability to diagnose difficult cases misses the mark and overlooks real innovation, experts say.
Nature – A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.
Emotionally intelligent AI can generate trust, motivate action, elevate the relationship between patients and their care teams, and drive meaningful change.
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The development of analgesic drugs targeting sodium channels NaV1.7 and NaV1.8 is described. FDA approval of the NaV1.8 antagonist suzetrigine presages an
Pain and Therapy – There is a high unmet need for safe and effective non-opioid medicines to treat moderate to severe pain without risk of…
The fine comes as the DNA testing firm, which filed for bankruptcy in March, is set to be sold to a new owner.
This is the same person that 23andMe customers originally trusted with their personal data, albeit under a much more opaque governance structure.
Technology could be a boon for science, but raises ethical concerns
The future of the genetic data owned by 23andMe is uncertain as the company undergoes a court-supervised sale.
