Key PointsCAR T cells induce a cellular and humoral immunodeficiency resulting in an initial susceptibility for bacterial and later viral infections.Severe
Andrew J. Cowan, MD, is an associate professor at the University of Washington and the Clinical Research Division of Fred Hutchinson Cancer Center in Seattle.…
Wiskott-Aldrich syndrome (WAS) is a rare X-linked disorder with highly variable clinical presentation. In this How I Treat article, Vallée and coauthors pr
Muna Al Jabri, Ali Sakhdari; A rare phenotype of peripheral T-cell lymphoma, NOS: coexpression of CD15, CD20, and T follicular helper markers in a DUSP22…
In this issue of Blood Advances, Shah et al1 provide an evidence-based proposal to harmonize the classification of TP53 mutant myelodysplastic neoplasms (M
Key PointsNivolumab plus relatlimab was overall safe, tolerable, and manageable with no unexpected safety signals or treatment-related deaths.The combinati
Key PointsIron overload in HFE-related hemochromatosis and thalassemia leads to reversal of the Vδ2+/Vδ2– ratio in the γδ T-cell compartment.Iron promotes
Key Points. BCMA antigen expression is controlled by the ubiquitin-proteasome system in a p97-dependent manner at the plasma membraneElevation of BCMA cell
Key PointsEarly use of daratumumab combinations in patients with MM admitted with kidney injury rapidly reduces sFLCs.Early initiation of daratumumab combi
Key PointsCREBBP mutations create a zombie enzyme that inhibits EP300 and blunts CD40-responsive chromatin loading and enhancer activation.Enforcing CD40 s
