Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus.
Nature – Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment…
Nature Neuroscience – This study investigates how homeostatic mechanisms endow sensory representations in the auditory cortex with resilience against neuron loss. The map of sounds…
About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90% of these deaths…
Nature Communications – Here, the authors perform a machine learning meta-analysis of Parkinson’s disease (PD) classification based on microbiome features, showing that the accuracy of…
Nature Neuroscience – The brain and body are necessarily connected. Here the authors show that brain blood flow and electrical activity are coupled with systemic…
Computational and experimental studies of drug resistance evolution give insights into why some bacteria become resistant.
For decades, scientists have used near-infrared light to study the brain in a noninvasive way. This optical technique, known as fNIRS (functional near-infrared spectroscopy), measures…
Nature Communications – Successful skeletal muscle regeneration involves a complex and finely tuned inter-cellular response. Here, by using spatial transcriptomics, the authors identify an…
Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol…
Scientific Reports – Surgical considerations towards inducing proprioceptive feedback in dental implants
