Therapeutics targeting the epidermal growth factor receptor (EGFR) are used for many cancer types, but they have notable side effects, including a potentially severe and disfiguring skin rash. Klufa et al. discovered that the inhibition of EGFR interferes with the ability of skin stem cells to reestablish a secure barrier after it is broken in the process of hair eruption. This loss of skin…
Nature Reviews Clinical Oncology – DeepGEM, an artificial intelligence (AI)-based model, accurately predicts the presence of key genomic alterations in histological slides prepared from samples…
Nature Reviews Clinical Oncology – Accumulating evidence indicates that NUT carcinoma, a highly aggressive malignancy driven by NUTM1 fusions, is a rare form of squamous…
Nature Reviews Clinical Oncology – Paediatric acute myeloid leukaemia (AML) highlights the challenges of drug development for rare diseases, in which limited patient numbers and…
Nature Reviews Clinical Oncology – Perioperative chemotherapy superior to preoperative chemoradiotherapy for locally advanced EAC
Nature Reviews Clinical Oncology – Thermal ablation is safer than resection of colorectal liver lesions
Nature Reviews Clinical Oncology – Paediatric acute myeloid leukaemia (AML) highlights the challenges of drug development for rare diseases, in which limited patient numbers and…
Nature Reviews Clinical Oncology – Early promising results with addition of an ICI and an anti-angiogenic to TACE
Nature Reviews Clinical Oncology – Paediatric acute myeloid leukaemia (AML) highlights the challenges of drug development for rare diseases, in which limited patient numbers and…
Nature Reviews Clinical Oncology – Recent results from the phase III AQUILA trial demonstrate the benefit of fixed-duration monotherapy with daratumumab over observation in patients…
Nature Reviews Clinical Oncology – Recent results from the phase III AQUILA trial demonstrate the benefit of fixed-duration monotherapy with daratumumab over observation in patients…
