Glomerulonephritis in Pregnancy
Pregnancy triggers numerous physiological changes, including volume expansion, vasodilation, and changes in hormonal milieu, which are crucial in facilitating the kidneys’ adaption to pregnancy. These changes cause a decline in serum creatinine levels, which is most prominent in the second trimester, after which serum creatinine begins to stabilize. Glomerulonephritis during pregnancy may present as acute kidney injury (AKI) or exacerbate preexisting chronic kidney disease (CKD). CKD can affect both maternal and fetal well-being, but data on glomerulonephritis in pregnancy remain limited. Unique kidney-related pathophysiological changes in pregnancy are explored, with a focus on the evaluation and management of glomerulonephritis in this context.
