From Blood to Vessel: Lipid Ratios in Pulmonary Hypertension
Circulating metabolites represent the integrated effects of gene expression, enzymatic activity, and environmental influences across different tissues. Compared with gene transcripts and proteins, they are considered more closely related to the extant pathology, making them particularly valuable as biomarkers for assessing disease risk and gaining insights into pathobiological mechanisms (1, 2). A growing body of evidence has demonstrated that pulmonary arterial hypertension (PAH) is characterized by
