Protein therapeutics such as antibodies require in-depth in vivo characterization during development and consequently account for a large proportio…
AI systems have attained superhuman performance across various domains. If the hidden knowledge encoded in these highly capable systems can be leve…
Nature Immunology – Stunnenberg et al. use a model of lipopolysaccharide injection in humans to characterize the transcriptomic landscape of bone marrow and blood immune…
Nature Human Behaviour – How does the brain encode complex movement sequences? Qi et al. reveal that the brain decomposes sequences into temporal states, each…
Hexosamine synthesis pathway and SCAP/SREBP-1 reciprocally enhance each other to drive malignant brain tumor growth.
Translational Psychiatry – Healthy sleep patterns and risk of hospitalization for infection: a large community-based cohort study
Nature Communications – Here, the authors characterize the epigenetic status of hybrid ecDNA in HPVOPC, identifying HPV oncogenes E6/E7 in hybrid ecDNA are flanked by…
This cross-sectional study analyzes the use of 10 no-cost preventive services by individuals with employer-sponsored health insurance, which may be threatened by the upcoming Kennedy…
Annals of Biomedical Engineering – High-frequency irreversible electroporation (H-FIRE) is a minimally invasive local ablation therapy known to activate the adaptive immune system and reprogram…
Hypertension Research – Clinical studies in Myxomatous Mitral Valve Disease dogs: most prescribed ACEI inhibits ACE2 enzyme activity and ARB increases AngII pool in plasma
Original Article from The New England Journal of Medicine — Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer
