Female Patients Have a Reduced Risk of Reoperation for… : Annals of Surgery
larly following open repair, potentially due to missed femoral hernias. However, this may not apply to laparoscopic repair, where all hernia orifices are routinely visualized. Methods: We conducted a nationwide, register-based cohort study utilizing prospectively collected data from the Danish Inguinal Hernia Database and national health registers. Female patients undergoing elective primary laparoscopic groin hernia repair were matched in a 1:3 ratio with male patients based on hernia type, defect size, age (±5 years), and follow-up time (±6 months). Cox proportional hazards regression was employed to assess the risk of reoperation for recurrence. A sensitivity analysis, which included the Charlson Comorbidity Index, was performed. Results: The matched cohort comprised 6,275 females and 18,825 males. Reoperation for recurrence occurred in 2.2% of females and 3.6% of males (P<0.001). Adjusted analyses indicated that females had a 41% lower risk of reoperation compared to males (adjuste
