Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced (armore…
Recently, a federal judge struck down an FDA rule on laboratory-developed tests. If this invalidation stands, it will have consequences for clinical care and the…
The benefits of automated insulin delivery are well established in type 1 #diabetes, but its efficacy and safety in type 2 diabetes have been uncertain.…
When a dying patient’s parents refuse to give up hope, her physician opts to hope with them, going to unusual lengths to provide a last…
Pegivirus hominis, a common virus that has not been linked to specific diseases, was detected in CSF, serum, and brain tissue from four patients with…
In phase 2 trials involving patients with stage 2 or 3 fibrosis caused by metabolic dysfunction–associated steatohepatitis (MASH), efruxifermin, a bivalent fibroblast growth factor 21…
The Trump administration’s proposed 15% cap on indirect-cost rates for National Institutes of Health grants risks upending the paradigm that underpins American leadership in medical…
Daratumumab, an anti-CD38 monoclonal antibody, has been approved for the treatment of multiple myeloma. Data are needed regarding the use of daratumumab for high-risk smoldering…
Inadequate payment is just one of many factors that negatively affect daily practice and contribute to burnout among primary care physicians. Also problematic are growing…
The Trump administration’s proposed 15% cap on indirect-cost rates for National Institutes of Health grants risks upending the paradigm that underpins American leadership in medical…
