The past century has been characterized by intensive efforts, within both academia and the pharmaceutical industry, to introduce new treatments to individuals with rheumatic autoimmune inflammatory diseases (RAIDs), often by ‘borrowing’ treatments already employed in one RAID or previously used in an entirely different disease, a concept known as drug repurposing. However, despite sharing some…
Oncogene – Human CSPG4-targeting CAR-macrophages inhibit melanoma growth
Nature Communications – Ancestral bias in cancer genomic datasets limits the effectiveness of precision medicine. Here, the authors introduce PhyloFrame, a machine learning framework that…
Nature Medicine – Exploratory post hoc analysis of molecular residual disease from the ADAURA trial of adjuvant osimertinib in patients with resected EGFR-mutated stage IB–IIIA…
Journal of Perinatology – Management of the patent ductus arteriosus among infants born at 23 to 32 weeks’ gestation between 2011 to 2022: a report…
Scientific Reports – Unique events improve episodic richness, enhance mood, and alter the perception of time during isolation
Nature Communications – Virtual nature exposure reduces self-reported pain and is associated with decreased brain responses linked to somatosensory and nociceptive processing, providing new…
Nature Reviews Gastroenterology & Hepatology – The burden of liver disorders increases worldwide as does the necessity for new treatments. This Review discusses cell therapy…
Scientific Reports – An osteobiography of a celebrity chimpanzee reflects the changing roles of modern zoos
Nature Reviews Cancer – ALK genetic alterations drive various malignancies through aberrant tyrosine kinase activation, promoting oncogenic cell growth and survival. Here, Voena et al.…
Nature Neuroscience – Cholinergic interneurons act at nicotinic receptors to depress dopamine release, interrupting its relationship to dopamine neuron firing and supporting an inverse scaling…
