Defining a novel DYRK1A-gp130/IL-6R-pSTAT axis that regulates Th17 differentiation
Abstract. Dysregulated differentiation of naïve CD4+ T cells into T helper 17 (Th17) cells is likely a key factor predisposing to many autoimmune diseases.
Abstract. Dysregulated differentiation of naïve CD4+ T cells into T helper 17 (Th17) cells is likely a key factor predisposing to many autoimmune diseases.
Abstract. Right heart catheterization (RHC) plays a pivotal role across the spectrum of heart failure, from ambulatory patients to those in cardiogenic sho
Abstract. Sepsis remains the most common cause of death in critically ill patients worldwide and the most frequent non-cardiac disease diagnosed in the Cor
In people prescribed >20 mg/day prednisone, vaccine responses are reduced; while for those taking 7 to 20 mg/day the evidence remains inconclusive. Vacc
Amyotrophic lateral sclerosis (ALS) has been linked to physical exercise, but it is unclear who may be at risk and through what mechanism. O’Brien et…
Erwan Donal, MD, PhD, Prayuth Rasmeehirun, MD, Marina Petersen Saadi, MD; Time to Rethink Timing: Diastolic Dysfunction as a Trigger for Intervention in AR
AbstractBackground. Malignant pericardial effusions are often linked to metastases from solid tumours, such as those in the lung or breast, or haematologic
AbstractBackground and Aims. Immune checkpoint inhibitors (ICI) are associated with life-threatening myocarditis but milder presentations are increasingly
Heart failure (HF) and atrial fibrillation (AF) are closely intertwined, and the occurrence of AF in patients with chronic HF is related to worse prognosis
AbstractBackground. Malignant pericardial effusions are often linked to metastases from solid tumours, such as those in the lung or breast, or haematologic
AbstractObjective. Thyroid cancer (TC) is the most common endocrine malignancy, with 90%-95% of the cases representing non–medullary thyroid cancer (NMTC).