Deep tissue imaging of cancer in the infrared
Nature Reviews Cancer – Ali Sonay describes the development of an image-guided surgical approach that uses a commercially available dye, CJ215, to improve the real-time detection and precise…
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Nature Reviews Neurology – Genetic studies in Africa can provide a unique window into hereditary neurological diseases (HNDs). This Review highlights the benefits and challenges…
Gene therapy for cardiac arrhythmias
Nature Reviews Cardiology – In this Review, Ackerman and colleagues describe the rationale for gene therapy to treat cardiac arrhythmias; discuss advantages and disadvantages of…
Clonal tracing with somatic epimutations reveals dynamics of blood ageing
Nature – The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone,…
Revealing secrets of human genetic variation with population databases
Nature Reviews Genetics – In this Journal Club, Nicole Lake recalls a 2016 paper by Lek et al., as part of the Exome Aggregation Consortium,…
Gene therapy for cardiac arrhythmias
Nature Reviews Cardiology – In this Review, Ackerman and colleagues describe the rationale for gene therapy to treat cardiac arrhythmias; discuss advantages and disadvantages of…
Association of plasma homocysteine with morning blood pressure in patients with essential hypertension
Hypertension Research – Association of plasma homocysteine with morning blood pressure in patients with essential hypertension
A health boost from the arts
Nature Medicine – As momentum grows to enlist the arts for better health, critics ask whether the practice is getting ahead of the evidence.
Programmable control of spatial transcriptome in live cells and neurons
Nature – CRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in…
How cancer reduces motivation
Nature Reviews Cancer – In addition to its physical symptoms, cancer cachexia — a severe wasting syndrome — also leads to fatigue, apathy and depression.…