This randomized clinical trial assesses whether reducing supplemental oxygen to a peripheral oxygen saturation target of 90% would reduce mortality among critically ill adults receiving mechanical ventilation compared with usual care.
We have entered the era of precision oncology medicine, led by technical advances in nucleic acid and protein high throughput analyses and generation of targeted…
This study attempts to investigate factors associated with late-onset epilepsy in people with cognitive decline.
This multinational cohort study examined whether an artificial intelligence (AI) algorithm could predict heart failure risk from noisy single-lead electrocardiograms.
This randomized clinical trial compares the effectiveness of initiating oral naltrexone vs extended-release injectable naltrexone on reduction in alcohol use and health care utilization among…
This prognostic study evaluates the predictive performance of combining genetic variants and developmental milestones to predict intellectual disability in autistic children.
This Viewpoint offers an account of the events surrounding the discovery of the biological action of glucagon-like peptide-1 and the roles of the individuals who…
This cohort study examines the use of minimizing terms in adverse event reporting in multiple myeloma randomized clinical trials published between 2015 and early 2023.
This cross-sectional study examines trends and disparities in self-reported maternal physical and mental health between 2016 and 2023 in the US.
This comparative effectiveness study investigates anti–vascular endothelial growth factor vs anti–epidermal growth factor receptor therapy in second-line treatment among patients with RAS/RAF wild-type, right-sided cancer.
This cohort study examines whether paternal exposure to metformin during spermatogenesis is associated with major congenital malformations in children.
