Computational analysis of continuous body temperature provides early discrimination of graft-versus-host disease in mice | Blood Advances | American Society of Hematology
We implanted wireless core body temperature sensors intraperitoneally in 28 mice: 17 receiving allo-HCT, 10 receiving syn-HCT, and 1 serving as a naive (no-HCT) control. Two doses of splenic T cells were used to induce aGVHD of lesser and greater severities: LowT (1 × 106 cells; n = 7 allo-HCT mice [AlloLowT] and n = 5 syn-HCT mice [SynLowT]) and HighT (3…