This randomized clinical trial compares the effect of early intensive and sustained vasodilation (using nitrates, hydralazine, renin-angiotensin inhibitors, and sacubitril-valsartan) vs usual care on a composite outcome of all-cause mortality and acute heart failure rehospitalization at 180 days…
This randomized clinical trial assesses the effect of metformin on knee pain among patients with symptomatic knee osteoarthritis and overweight or obesity.
Among social determinants of health, while the effect of patient characteristics on health outcomes has been explored extensively, the effect of surgeon characteristics has only…
This study estimates the number of cases and complications in the US under scenarios of declining childhood vaccination for measles, rubella, poliomyelitis, and diphtheria.
This randomized clinical trial assesses the effect of metformin on knee pain among patients with symptomatic knee osteoarthritis and overweight or obesity.
This cohort study evaluated the association between medical debt among US adults and forgoing mental health care due to cost in the subsequent year.
Among social determinants of health, while the effect of patient characteristics on health outcomes has been explored extensively, the effect of surgeon characteristics has only…
This randomized clinical trial examines the efficacy of high-dose cholecalciferol (vitamin D) as monotherapy in reducing disease activity in patients with clinically isolated syndrome typical…
This JAMA Insights discusses lipoprotein(a), including factors associated with elevated lipoprotein(a) levels, how to manage them, and atherosclerotic cardiovascular disease risk.
This Viewpoint discusses an opportunity to promote safeguarding, expanding, and modernizing the national health survey infrastructure as a crucial part of a comprehensive approach to…
This JAMA Patient Page describes atrial fibrillation and its symptoms, diagnosis, and treatment.
