BackgroundMitral valve prolapse (MVP) is highly prevalent in Marfan syndrome (MFS), but its associations with significant valvular regurgitation, the need for mitral valve (MV) surgery or elective …
Sarcopenia is the loss of muscle strength, mass, and function, which is often exacerbated by chronic comorbidities including cardiovascular diseases, chronic kidney disease, and cancer.…
Intraoperative transesophageal echocardiography is used with increasing frequency in cardiac surgery for monitoring and diagnostic purposes. Recent data have shown the impact of improved outcomes…
BackgroundThe role of iron deficiency (ID) in ST‐segment–elevation myocardial infarction (STEMI) remains unclear. This study aimed to assess whether ID is associated with impaired myocardial…
BACKGROUND: The SPAN (Stroke Preclinical Assessment Network) is a confirmatory trial platform to test the efficacy and safety of candidate cerebroprotective interventions in acute stroke.…
BACKGROUND: Despite the significant global impact of the COVID-19 pandemic, limited studies have investigated the long-term cardiovascular sequelae of SARS-CoV-2 infection, particularly among Asian populations.…
Neonatal stroke, occurring within the first 28 days after birth, affects >1 in every 2500 newborns. The weekly adjusted risk of stroke in a term…
Circulati on: Heart Failure is proud to launch a new and exclusive educational series tailored for current advanced heart failure fellows and early-career attendings (within…
Inflammation is central in heart failure with preserved ejection fraction (HFpEF) pathogenesis, but the mechanisms remain elusive. 1 Clonal hematopoiesis (CH) is associated with systemic…
The win ratio is a method for analyzing a hierarchical composite outcome. It has been most widely used in randomized clinical trials (RCTs) in cardiovascular…
BackgroundHypertension is a major risk factor for cardiovascular disease (CVD). The SPRINT (Systolic Blood Pressure Intervention Trial) study demonstrated that intensive lowering of systolic blood…
