Recent data from National Health Service (NHS) weight clinics in England show that a disproportionate number of referrals originate from the most deprived areas, with some children having BMIs over 40 kg/m2 or even 50. The analyses were conducted by researchers from universities in Leeds, Sheffield, and Bristol, and presented at the European Congress on Obesity in May, 2025.
The was an excess of germline variants classified as potentially pathogenic variants in patients with non-European ancestry, which might impede the diagnostic process. Improved variant…
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Addressing obesity must be at the heart of the global NCD response if we are to stem the tide of rising NCDs.
Once-daily fixed-ratio combination therapies of basal insulin and a GLP-1 receptor agonist such as insulin degludec with liraglutide (IDegLira) and insulin glargine U100 with lixisenatide…
In adults with inadequately controlled type 2 diabetes on daily basal insulin therapy, once‑weekly IcoSema showed superiority to once-weekly icodec alone in changes in HbA1c…
Once-weekly IcoSema achieved non-inferior HbA1c reduction and superiority in change in bodyweight, weekly total insulin dose, and hypoglycaemia rates versus daily BBT, suggesting that there…
Advances in cardiovascular disease prevention are often hailed as one of the major public health accomplishments of the past 50 years. The progress achieved is…
Weekly LYN-005 provided sustained release of risperidone at therapeutic concentrations with similar bioavailability to immediate-release risperidone. Patients remained clinically stable and no unexpected safety signals…
Central hypothyroidism is a rare disorder resulting from impaired thyroid hormone production due to deficiencies in TSH secretion from the pituitary or TRH secretion from…
