Cellular Therapies Begin to Make Their Mark in Solid Tumors
OncLive spoke with experts working to develop cellular therapies in solid tumors to gain insights into their current standing and future in the space.
OncLive spoke with experts working to develop cellular therapies in solid tumors to gain insights into their current standing and future in the space.
Vepdegestrant NDA under FDA review in ESR1-mutated breast cancer, Oncomine Dx Target Test gets greenlit as zongertinib companion diagnostic in NSCLC.
Treatment with casdatifan in combination with cabozantinib produced responses and was safe in patients with pretreated clear cell renal cell carcinoma.
Joshua K. Sabari, MD, discusses the design of the phase 1/2 ARROS-1 study, as well as key efficacy data with zidesamtinib in ROS1 fusionâpositive NSCLC.
Daniel DeAngelo, MD, PhD, shares the rationale behind a meta analysis of asparaginase regimens vs hyperâCVAD in adult and AYA patients with ALL.
Neoadjuvant olaparib plus carboplatin led to a high RCB 0/1 rate in BRCA1/2-mutated, HRD+ TNBC.
TAR-200 was found to be highly effective in treating select patients with bladder cancer whose tumors were previously unresponsive to therapy.
Bortezomib plus mitoxantrone hydrochloride liposome and dexamethasone produced responses with manageable safety in relapsed/refractory myeloma
Nemvaleukin alfa produced a disease control rate of 50% in advanced melanoma and RCC.
The development of SGR-2921 in relapsed/refractory AML and higher-risk MDS was discontinued followed by 2 patient deaths.
Matthew Hadfield, DO, discusses how hematology/oncology fellows should approach the interpretation of clinical trial data.