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Exercise based cardiac rehabilitation for atrial fibrillation: Cochrane systematic review, meta-analysis, meta-regression and trial sequential analysis
Objective To undertake a contemporary review of the impact of exercise based cardiac rehabilitation (ExCR) for patients with atrial fibrillation (AF). Data sources CENTRAL, MEDLINE,…
Association between ultra-processed food consumption and lung cancer risk: a population-based cohort study
Background The evidence on associations between ultra-processed foods (UPF) and lung cancer risk is limited and inconsistent. Research question Are UPF associated with an increased…
Risk of adolescent cigarette use in three UK birth cohorts before and after e-cigarettes
Objective Longitudinal data from three UK birth cohorts (born in 1958, 1970 and 2001) were used to (1) document the historic decline in adolescent cigarette…
Authors | Considerations In Medicine
Considerations in Medicine reviews the background, latest clinical developments, and future research perspectives for selected areas of medicine where an expert overview for busy clinicians…
Direct-to-consumer self-tests sold in the UK in 2023: cross sectional review of information on intended use, instructions for use, and post-test decision making
Objectives To review the information provided for self-test devices sold in high street shops in the UK and to assess their suitability for informed decision…
Evaluating GLP-1 receptor agonists versus metformin as first-line therapy for reducing dementia risk in type 2 diabetes
Introduction No direct comparisons have evaluated glucagon-like peptide-1 receptor agonists (GLP-1 RAs) versus metformin as first-line antidiabetic therapy for preventing dementia in patients with type…
Economic burden of PTSD in the UK: a systematic review and economic analysis
Objectives Post-traumatic stress disorder (PTSD) constitutes a significant anxiety disorder that exerts substantial societal and familial impacts, while concurrently imposing an additional as well as…
The impact of local anesthetic systemic toxicity advisories on reporting to the National Poison Data System (NPDS)
Introduction In 2010, multiple anesthesia societies introduced recommendations for treating local anesthetic systemic toxicity, but the impact of those recommendations is uncertain. Objective To test…
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