Brentuximab vedotin in the treatment of CD30+ PTCL | Blood | American Society of Hematology
You do not currently have access to this content.
You do not currently have access to this content.
Valentin Goede, Kirsten Fischer, Sandra Robrecht, Adam Giza, Martin JS Dyer, Michael J. Eckart, Lothar Müller, Lukáš Smolej, Nadine Kutsch, Anna-Maria Fink
AbstractBackgroundIn the STOP-CA (Statins to Prevent the Cardiotoxicity From Anthracyclines) trial, atorvastatin preserved the left ventricular ejection fraction among patients with lymphoma treate…
Key PointsVenetoclax (14 days) + azacitidine regimen was well tolerated in patients with treatment-naive HR MDS, with no unexpected safety findings.The reg
Key PointsDisruption of antioxidant selenoprotein synthesis exhibited significant defects in B lymphocyte development and HSC function.Cell context and lin
We optimized a 42-parameter panel for profiling human immune cells in peripheral blood, identifying over 80 immune subsets. The panel outperforms other published panels on…
Key PointsB-cell maturation antigen–directed CAR-T therapy in patients with MM and CNS involvement is feasible without excess neurotoxicity.Data support CN
Key PointsDetection of mNPM1 MRD by NGS using DNA overcomes several limitations of RT-qPCR and is therefore an attractive alternative assay.The prognostic
Key PointsLenalidomide induces immunomodulating responses through the activation of dsRNA-sensing pathway.ADAR1 drives lenalidomide resistance in MM via th
Key Pointsα-Actinin-1 deficiency in MKs is associated with low platelet count and leads to impaired platelet function and thrombosis.α-Actinin-1 is critica
Key PointsOur study discovered new regulators of ruxolitinib response in Ph-like ALL, including c-MYC as a therapeutically targetable codependency.A progno