Belzutifan Prolongs Quality-Adjusted Time Without Symptoms or Toxicity in Advanced RCC
Treatment with belzutifan increased the time without progression or toxicity vs everolimus in patients with advanced RCC.
Treatment with belzutifan increased the time without progression or toxicity vs everolimus in patients with advanced RCC.
KIM-1 levels have shown the ability to predict therapeutic benefit in patients with renal cell carcinoma.
The FDA issued a CRL to the application for glofitamab plus chemotherapy in relapsed/refractory diffuse large B-cell lymphoma.
Luspatercept plus a concomitant JAK inhibitor didn’t meet the primary end point of 12-week RBC transfusion independence in myelofibrosis-associated anemia.
PF-07248144 is a first-in-class selective inhibitor of KAT6A and KAT6B that has displayed the ability to suppress ER expression in a preclinical study.
Mats Jerkeman, MD, discusses long-term follow-up data of the Nordic MCL2 and MCL3 trials in younger patients with mantle cell lymphoma.
High levels of CD163-positive TAMs and exhausted CD8-positive TILs could potentially affect efficacy results in metastatic RCC by reprogramming TAMs.
JSKN003 demonstrated tolerability and antitumor activity in heavily pretreated HER2-positive breast cancer.
In an OncLive Peer Exchange, expert investigators convened to discuss the treatment landscape of early-stage NSCLC from a multidisciplinary perspective.
Cyrus M. Khan, MD, discusses the role of second-generation BTK inhibitors and their implications for clinical practice in the CLL treatment paradigm.
Metastasis-directed radiotherapy without systemic therapy demonstrated an improved safety profile vs immunotherapy and tyrosine kinase inhibitors.