A 63-year-old man with a past medical history of ischemic cardiomyopathy and multiple heart failure hospitalizations was admitted to our Institute for worsening exertional dyspnea (New York Heart Association functional class III). Transesophageal echocardiography revealed severe left ventricular (LV
AbstractBackgroundLeft ventricular pseudoaneurysm (LVPA) is a rare yet potentially life-threatening complication following myocardial infarction or cardiac surgery. Although surgical repair has tra…
AbstractBackgroundCardiovascular diseases (CVDs) are the leading cause of global mortality. Understanding epidemiologic trends in the modifiable risk factors driving CVDs is essential in designing …
Highlights •We developed a novel bispecific antibody, InflamAb, designed to target the IL-1R1 for cell entrance and inhibit the intracellular NLRP3 inflammasome.•InflamAb potently inhibits NLRP3…
AbstractBackgroundPulsed-field ablation (PFA) may be beneficial for the treatment of atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM).ObjectivesThe goal of this study was…
AbstractPositron emission tomography (PET)/computed tomography is a major imaging strategy for cardiovascular disease characterization. Whereas multiple radioisotopes can be used for PET imaging of…
AbstractBackgroundFractional flow reserve (FFR) and the instantaneous wave-free ratio (iFR) identify arteries that benefit from percutaneous coronary intervention (PCI). FFR or iFR gradients on pul…
AbstractVasoplegia syndrome is a specific form of vasodilatory shock encountered in patients who undergo cardiac surgery, most commonly with cardiopulmonary bypass, which is characterized by…
AbstractBackgroundCardiometabolic diseases (CMD) include coronary heart disease, stroke, and diabetes. Patients who have ≥2 CMD are defined as cardiometabolic multimorbidity (CMM). CMD and CMM have…
AbstractBackgroundPostsurgical pseudoaneurysms at the anastomosis of saphenous vein grafts are uncommon and may result in catastrophic complications owing to their fragility and the risk of…
AbstractBackgroundTruncating titin variants (TTNtvs) are the most prevalent cause of inherited dilated cardiomyopathy. Occurrence of different ventricular arrhythmia (VA) subtypes, including premat…
