Nutrient composition and caloric intake have traditionally been used to devise optimized diets for various phases of life. Adjustment of meal size and frequency have emerged as powerful tools to ameliorate and postpone the onset of disease and delay aging, whereas periods of fasting, with or without reduced energy intake, can have profound health benefits. The underlying physiological processes…
The rise of ChatGPT and its rivals is undermining the economic bargain of the internet
This JAMA Internal Medicine Patient Page describes how glucagon-like peptide-1 (GLP-1) receptor agonists work and what behaviors to adopt while using them.
This JAMA Internal Medicine Patient Page describes how glucagon-like peptide-1 (GLP-1) receptor agonists work and what behaviors to adopt while using them.
GLP-1 medicines, initially developed for blood glucose and weight control, improve outcomes in people with cardiovascular, kidney, liver, arthritis, and sleep apnea disorders, actions mediated…
This cohort study evaluates the association of glucagon-like peptide 1 receptor agonists (GLP-1RAs) semaglutide and tirzepatide with incidence of neurodegenerative and cerebrovascular diseases in patients…
Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma…
The Global Neurodegeneration Proteomics Consortium is a multi-national database that aims to leverage proteomics and clinical data to understand and improve …
Nature Medicine – Proteomic analysis of paired cerebrospinal fluid and plasma samples from 2,171 individuals drawn from multiple cohorts, including the Global Neurodegeneration Proteomics…
Nature Medicine – The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic…
Nature Medicine – The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic…
