This cohort study of participants with dominantly inherited Alzheimer disease examines the rates of change in cerebrospinal fluid levels of total tau (tTau) and phosphorylated tau 181 (pTau181) across the disease course and how the rates of change are associated with brain atrophy.
This secondary analysis of the Phacogoniotomy vs Phacotrabeculectomy (PVP) randomized clinical trial investigates if intraocular pressure reduction with phacogoniotomy is noninferior to phacotrabeculectomy in advanced…
This cross-sectional study examined the scale and scope of value-based state-directed payments in Medicaid managed care.
This JAMA Patient Page describes typhoid fever and its symptoms, vaccination options, and disease risk reduction measures.
This study compares premature study termination rates in placebo groups of high-quality randomized clinical trials across 9 major psychiatric disorders, focusing on total dropouts, dropouts…
This nonrandomized clinical trial examines the efficacy and safety of dasatinib in combination with chimeric antigen receptor T cells as frontline therapy in adults with…
This randomized clinical trial evaluated the effectiveness of finerenone in patients with heart failure and mildly reduced ejection fraction or preserved ejection fraction across the…
This Perspective examines how transitioning from metered-dose inhalers to dry-powder and soft-mist inhalers could reduce inhaler-related emissions, thereby moderating inhalers’ contribution to climate change.
This cohort study evaluates if neighborhood deprivation is associated with thicker (greater than 2 mm) cutaneous melanoma diagnosis after controlling for individual-level characteristics in the…
This systematic review and individual participant data met-analysis assesses the cancer-related and survival outcomes in solid organ transplant recipients with advanced-stage cancer treated with immune…
This JAMA Insights proposes solutions to help reduce the risk of heat-related illnesses among workers.
