404 Error
[Skip to Content Landing] The page you’re looking for cannot be found. Please check the address, or try visiting the home page. Return Home
Related Articles
Exercise-Induced Dyspnea in an Older Woman With a History of Coronary Artery Disease
An older woman with a history of coronary artery disease presents with dyspnea upon exertion. A transthoracic echocardiogram reveals severe mitral regurgitation, and an electrocardiogram…
Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation
This cross-sectional study investigates the prevalence of heart failure with preserved ejection fraction (HFpEF) in severe isolated secondary tricuspid regurgitation and the performance of noninvasive…
Simultaneous or Rapid Initiation of Combination Therapy for Heart Failure With Preserved Ejection Fraction
This Viewpoint recommends simultaneous or rapid sequence initiation of combination therapy with 3 specific classes of medication for heart failure with mildly reduced ejection fraction…
Valsartan and Cardiac Remodeling in Early-Stage Hypertrophic Cardiomyopathy
This prespecified substudy of the VANISH randomized clinical trial evaluates the treatment effects of valsartan on myocardial structure, function, and tissue parameters in early-stage sarcomeric…
LDL Cholesterol–Lowering Strategy in ASCVD
This systematic review and individual patient data meta-analysis investigates the association of an alternative low-density lipoprotein (LDL) strategy with differences in long-term efficacy and safety…
Heart Failure in Zero Gravity—External Constraint and Cardiac Hemodynamics
In this case series study, pulmonary artery systolic, diastolic, and mean pressures of 2 participants with obesity and heart failure with preserved ejection fraction were…
Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis
This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.
Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis
This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.
Outcomes of Balloon-Expandable Transcatheter Aortic Valve Replacement in Younger Patients
This cohort study assesses characteristics and outcomes of younger patients undergoing transcatheter aortic valve replacement.
Olpasiran, Oxidized Phospholipids, and Systemic Inflammatory Biomarkers
The OCEAN(a)-DOSE multicenter randomized clinical trial among 281 patients with atherosclerotic cardiovascular disease assesses the effects of olpasiran on oxidized phospholipids, high-sensitivity interleukin 6, and…